Widespread Changes in Synaptic Markers as a Function of Sleep and Wakefulness in Drosophila

Science. 2009 Apr 3;324(5923):109-12 Gilestro GF, Tononi G, Cirelli C Sleep is universal, strictly regulated, and necessary for cognition. Why this is so remains a mystery, though recent work suggests a link between sleep, memory, and plasticity. However, little is known about how wakefulness and sleep affect synapses. Using Western blots and confocal microscopy in [...]